Hexamethylenetetramin-sodium acetate double salt.



PETER- BERGELL, Oi BElL-l;

; rlrrss lRhLlAN Y, ASSIGHOH JOilAlllZ A. WULFING, OF UERMQ Specification of Letiers IPa'sent.

Pctented Hair 7 1907.

Application filed December 18, 1906. Serial. No. 28,376. (Elyse-linens.)

To all [lib/fill it may can/corn.-

Bc it known that 1, PETER BERGELL, & Sill)- jccl; oi thc Emperor oi Geri'nony, and. zi res1- dentof Berlin,- in the Kingdom of lrussis. German liln'i'pirc, have invcntod certain new and useful .lnipmvciucuts in Processes for lroducinr :illoxzunothylenetctromin Sodium Accmle Douhlc Sail, of which tho lolloiriiig a" specification.

This lnVBllLlOXl los roliorcnco to the production of av double salt composed of hexamethylenetolI'm-min and acetate of sodium and the process of making some. l have found that those two substances will combine under certain conditions and. in certain proportions to form n uniform double salt which contains one molecular proporiion o'l licxn'iorhylci'iototramin "no two molecular pro portions of acetstoi'i-E sodium and six molecules oi Waller. This new chemical com-- pound is directly formed when the shove i0 form this one double salt contsinin ono molecule of the hose to two molecules of the. salt and each of tho hitter roioins its Hires molecules oi Writer of crystallizziiion.

The process of forming the new compound finds expression in tho following copation:

The now compound crystsllizes in pure white cryscals Whlff-l'l have the form-i of lanoots or needles. When melted 'hllC sol;- stonco sinl'crs slightly together shove 62 C and zit 118 C itfoams up and melts with loss of water of crystallization. This shows plainly that thc new double salt dillers distinctly from its components, the acetate of sodium with or without Water of crystallization as well as the horas-methylenetctrcniin.

The solubility of the new substance Water in alcohol hut insoluble in other.

of ordinary temperature also proves that it. is a choi'i'iically well defined and uniform. com pound. 100 parts of the double will dissolvo in loss than parts of indie-r of 15 1 The solo hi i} of acotcl'o of sodium containi'li'lziil'ion is mnsiderslily ci'mipound contains almost 6 scotzitc of Sljl'lllllll containing water 0 I ballizsrion the solubility '11 wow may servo as a reaction to Provo the idemi of the new compound. in hot water 53 ps1 01" the now ooi'iipoimd will dissolve in loss than 2 poi-"ts of: Water. Tho new suhstmico is also soluble B on zone or chloroform dissolvo onl the owsnic ha-so ol the double salt in the mmuicr as is the case, say, with the: known doiddo of call'cin. and i3. l rvc as s milily may practical qiisntitstl ivii analysis for x Allqslios and mineral acids (.lccomposo :ho new double salt.

The new compound shows both cho" iiosl and medicinal advsiimgcs over hoxznhci-lwl- .enototrzimin or other so ipounds oi the t possessc the proper to crysmllizc to o groat-cr extent, liaison {l- I'Q-GEEh U taste and shows by virtue of the combination with 21ccall) of sodium a much greater diuretic ell'oct. The new compound may be n'izidc to still greater advantage:- whcn lire oily produced from lormsldohydc, ammonia, and assists ol sodium of tho respective inch-molar proportions with a. small surplus of smmonizvin a 'more economical manner and of the purity as if licxaimothyloiictoirimiin is l" st synthetically prepared from lori'iisldohydo and ammonia and then combined with. acetate of sodium.

Tho invention may be carried into practice in. substantially the following manner: 14

hilovrmns of hoxo-niofihvlcnctctrsmin are dissolved in water with 27.2 kilograms of scewto oi' sodium containing water of crystallization and than evaporated in a vacuum until. crystallization sets in. -On cooling the mass forms a still paste of crystals which is sepmted from the mother in the usual manner. 0.2000 grams of the substance dried in the e: icoctor abovosulfiiric acid L111- til the w eig becomes constant will. yield, according to Kjeldsli-l, 26AM milligrams of mi.

trogen, equal no 13.02%. 0.5000 grams of The moves. 0? pmduifl a 21w: uni nomgwmnd, & doubiu F-(HHPU: aavxvn'wiizylmnsivmmam n remw a.

tmmin am? two nwim'uhxir p portions of as 1- fee of sodium and evaporating this solution x. a vucmun.

As 11- novei composition 01" nmttar a crys- 10 nmdicina-I impow E cumposed of 011 nmivuu'nr propormcm m hmamxebhylmcts CIT-uni!) and twn moieculm progmrtions of Mm mm of sodium melting at 138 "(3. with loss of win}? of crvsmllizaticm, sohibie in. iess than his u m m @111 of wam' of ordinary temperm tum and 1) 111002101, insoluble in ether while bzHZQ'l'H? and LwHmwfimm, dissmlw only the in; X a r :wfihylmn: trmzjxi n.

In witness xfl'lereof E have horaunto signed, my nmne this 3rd day of Dvcvmbar 906, in t hY pmsvnw of two subscribing witnesses.

PETER BERGELL. 

